Anti-CD147(Basigin)    polyclonal antibody  (Rabbit)               Catalog:1003-10             

Product Description: CD147 (Basigin) is a member of the immunoglobulin superfamily, with a structure related to the putative primordial form of the family. CD147 is a widely expressed membrane glycoprotein that plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. It stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS) and may target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. In vitro, CD147 promotes outgrowth of astrocytic processes.

Species Cross-reactivity:  Mouse 

Formulation:   0.6mg/ml

Application(s):   WB: 1:500

Storage Buffer: 1*TBS (pH7.4), 0.5%BSA, 25%Glycerol. Preservative: 0.05% Sodium Azide.
 
Storage Instruction: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
 
Purity: Immunogen affinity purified

  

Fig: Western blot analysis on   mouse embryo using anti-CD147 polyclonal antibody.

 

References:
1."Retina-specific expression of 5A11/Basigin-2, a member of the immunoglobulin gene superfamily."Ochrietor J.D., Moroz T.P., van Ekeris L., Clamp M.F., Jefferson S.C., deCarvalho A.C., Fadool J.M., Wistow G., Muramatsu T., Linser P.J.Invest. Ophthalmol. Vis. Sci. 44:4086-4096(2003)"
2."Basigin expression and regulation in mouse ovary during the sexual maturation and development of corpus luteum."Chang H., Ni H., Ma X.-H., Xu L.-B., Kadomatsu K., Muramatsu T., Yang Z.-M.Mol. Reprod. Dev. 68:135-141(2004)