CD24 antigen is a small heavily glycosylated,
glycosylphosphatidylinositol (GPI) linked cell surface protein. It
consists of a small protein core comprising 27 amino acids, which
is extensively glycosylated and is bound to the membrane via a
phosphatidylinositol anchor. The CD24 antigen is physiologically
expressed in developing or regenerating tissue, as well as in
granulocytes, keratinocytes and renal tubular epithelium. It
modulates B-cell activation responses. Signaling could be
triggered by the binding of a lectin-like ligand to the CD24
carbohydrates, and transduced by the release of second messengers
derived from the GPI-anchor.
Species Cross-reactivity: Mouse , Rat
Storage Buffer: 1*TBS (pH7.4), 0.5%BSA, 25%Glycerol.
Preservative: 0.05% Sodium Azide.
Storage Instruction: Store at +4°C after thawing.
Aliquot store at -20°C or -80°C. Avoid repeated freeze /
Purity: Immunogen affinity purified
Fig: Western blot analysis on mouse brain
membrane using anti-CD24 polyclonal antibody
1. Kay R, Rosten PM, Humphries RK. CD24, a signal transducer
modulating B cell activation responses, is a very short peptide
with a glycosyl phosphatidylinositol membrane anchor. J Immunol
1991; 147: 1412-1416
2. Aigner S, Ruppert M, Hubbe M, Sammar M, Sthoeger Z, Butcher
EC, Vestweber D, Altevogt P. Heat stable antigen (mouse CD24)
supports myeloid cell binding to endothelial and platelet P-selectin.
Int Immunol 1995; 7: 1557-1565