Anti-CD4  polyclonal antibody  (Rabbit)             Catalog:0108-6

Product Description: The CD4 gene encodes the T4 antigen, a glycoprotein of approximately 55 kDa, expressed on the surface of helper T lymphocytes.CD4 antigens are members of the immunoglobulin supergene family and are implicated as associative recognition elements in major histocompatibility complex class II-restricted immune responses. On T-lymphocytes they define the helper/inducer subset. CD4 antigens also serve as interleukin-15 receptors and bind to the HIV receptors, binding directly to the HIV envelope protein GP120.

Species Cross-reactivity:  Mouse

Formulation:   0.54 mg/ml

Application(s):   WB: 1:500

Storage Buffer: 1*TBS (pH7.4), 0.5%BSA, 25%Glycerol. Preservative: 0.05% Sodium Azide.
 
Storage Instruction: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
 
Purity: Immunogen affinity purified

  

Fig: Western blot analysis on mouse brain using anti-CD4 polyclonal antibody.

 

References:
1.Parnes J.R., Hunkapiller T.; "L3T4 and the immunoglobulin gene superfamily: new relationships between the immune system and the nervous system."; Immunol. Rev. 100:109-127(1987).
2.Gorman S.D., Tourvieille B., Parnes J.R.; "Structure of the mouse gene encoding CD4 and an unusual transcript in brain.";Proc. Natl. Acad. Sci. U.S.A. 84:7644-7648(1987).
3.Rudd CE.CD4,CD8and the TCR-CD3complex:a novel class of proˉtein-tyrosine kinase receptor.Immunol Today,1990,11(11):400-406.