Anti-Junctophilin-2, polyclonal antibody  (Rabbit)                   Catalog0407-9                    

Product Description: Junctophilin-2 (JPH2) is a cardiac specific member of the junctophilins, a newly characterized family of junctional membrane complex proteins important in physically approximating the plasmalemmal L-type calcium channel and the sarcoplasmic reticulum ryanodine receptor for calcium-induced calcium release. It acts probably by anchoring the plasma membrane and endoplasmic reticulum. JPH2 contributes to the construction of skeletal muscle triad junctions, and plays an essential role in heart development.

Species Cross-reactivity:  Human , Mouse , Rat

Formulation:   0.5 mg/ml

Application(s):    WB:1:2000 

Storage Buffer: 1*TBS (pH7.4), 0.5%BSA, 25%Glycerol. Preservative: 0.05% Sodium Azide.
 
Storage Instruction: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
 
Purity: Immunogen affinity purified

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Fig: Western blot analysis on mouse heart using anti-JPH-2 polyclonal antibody

 

References:
1.Takeshima, H., et al. 2000. Junctophilins: a novel family of junctional membrane complex proteins. Mol. Cell 6: 11-22.
2.Nishi, M., et al. 2003. Coexpression of Junctophilin type 3 and type 4 in brain. Brain Res. Mol. Brain Res. 118: 102-110.