Anti-Relaxin 3 receptor 1 polyclonal antibody  (Rabbit)               Catalog:0902-7 

Product Description: Relaxin-3 receptor 1 belongs to the G-protein coupled receptor 1 family, It’s binding of the ligand inhibit cAMP accumulation. Upon ligand binding, the relaxin receptors activate adenylate cyclases through Gs proteins. RXFP3 is known to be important to several functions of the central nervous system, especially sensory processing under stressful conditions.

Species Cross-reactivity:  Mouse 

Formulation:   0.52 mg/ml

Application(s):   WB: 1:5,000~1:10,000       ICC: 1:100~1:200

Storage Buffer: 1*TBS (pH7.4), 0.5%BSA, 25%Glycerol. Preservative: 0.05% Sodium Azide.
 
Storage Instruction: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
 
Purity: Immunogen affinity purified

  

Fig: Western blot analysis on mouse spinal cord (A) and mouse brain (B) using anti- Relaxin 3 receptor 1 polyclonal antibody.

 

References:
1. "Identification of relaxin-3/INSL7 as an endogenous ligand for the orphan G-protein coupled receptor GPCR135."Liu C., Eriste E., Sutton S., Chen J., Roland B., Kuei C., Farmer N., Joernvall H., Sillard R., Lovenberg T.W.J. Biol. Chem. 278:50754-50764(2003)
2. "The novel G-protein coupled receptor SALPR shares sequence similarity with somatostatin and angiotensin receptors."Matsumoto M., Kamohara M., Sugimoto T., Hidaka K., Takasaki J., Saito T., Okada M., Yamaguchi T., Furuichi K.Gene 248:183-189(2000)