Anti-ZFP-42/REX-1  polyclonal antibody  (Rabbit)               Catalog:0731-3 

Product Description: REX-1/Zfp-42 was initially described as a factor present at high levels in murine F9 teratocarcinoma stem cells (EC).The Rex-1 (Zfp-42) gene encodes a zinc finger family transcription factor which is highly expressed in mouse and human embryonic stem cells. It is one of several gene markers used to identify human stem cells. REX-1 is found in spermatocytes and primary oocytes during replication and may play a role in meiosis. Recently, the expression of REX-1 in normal epithelial tissue cells has been demonstrated.

Species Cross-reactivity: Mouse

Formulation:   0.5  mg/ml

Application(s):   WB: 1:1,000   

Storage Buffer: 1*TBS (pH7.4), 0.5%BSA, 25%Glycerol. Preservative: 0.05% Sodium Azide.
 
Storage Instruction: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
 
Purity: Immunogen affinity purified

  

Fig: Western blot analysis on F9 using anti-ZFP-42 polyclonal antibody

 

References:
1.Mongan N.P., Martin K.M., Gudas L.J.; "The putative human stem cell marker, Rex-1 (Zfp42): structural classification and expression in normal human epithelial and carcinoma cell cultures."; Mol. Carcinog. 45:887-900(2006).
2.Raman J.D., Mongan N.P., Liu L., Tickoo S.K., Nanus D.M., Scherr D.S., Gudas L.J.; "Decreased expression of the human stem cell marker, Rex-1 (zfp-42), in renal cell carcinoma."; Carcinogenesis 27:499-507(2006).