(Smooth Muscle) polyclonal antibody
Description: Actins are highly conserved
proteins expressed in all eucaryotic cells. Actin filaments form
part of the cytoskeleton and play essential roles in regulating
cell shape and movement. Six distinct actin isotypes have been
identified in mammalian cells. Each is encoded by a separated gene
and is expressed in a developmentally regulated and
tissue-specific manner, alpha and beta cytoplasmic actins are
expressed in a wide variety of cells; whereas, expression of alpha
skeletal, alpha cardiac, alpha vascular, and gamma enteric actins
are more restricted to specialized muscle cell type. Smooth muscle
alpha actin is of further interest because it is one of a few
genes whose expression is relatively restricted to vascular smooth
muscle cells. Further more, expression of smooth muscle alpha
actin is regulated by hormones, cell proliferation , and altered
by pathological conditions including oncogenic transformation and
Human , Mouse
Storage Buffer: 1*TBS (pH7.4), 0.5%BSA, 25%Glycerol.
Preservative: 0.05% Sodium Azide.
Storage Instruction: Store at +4°C after thawing.
Aliquot store at -20°C or -80°C. Avoid repeated freeze /
Purity: Immunogen affinity purified
Fig: Western blot analysis on Mouse
Heart using anti-a-Actin polyclonal antibody
1. The MGC Project Team. Genome Res. 14:2121-2127(2004).
2. Leader D.P., Gall I., Campbell P.C. Biosci. Rep.
3. Carninci P., Kasukawa T., Katayama S.etc. Science