Anti-BMP2 polyclonal antibody  (Rabbit)             Catalog:0806-2     

Product Description: BMP-2 belongs to the TGF-β superfamily of proteins. BMP-2 plays an important role in the development of bone and cartilage. It is involved in the hedgehog pathway, TGF beta signaling pathway, and in cytokine-cytokine receptor interaction. It is involved also in cardiac cell differentiation and epithelial to mesenchymal transition. Implantation of BMP-2 in a collagen sponge induces new bone formation and can be used for the treatment of bony defects, delayed union, and non-union.

Species Cross-reactivity:  Human , Mouse , Rat

Formulation:   0.78mg/ml.

Application(s):   WB: 1:5,000

Storage Buffer: 1*TBS (pH7.4), 0.5%BSA, 25%Glycerol. Preservative: 0.05% Sodium Azide.
 
Storage Instruction: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
 
Purity: Immunogen affinity purified

  

Fig: Western blot analysis on mouse kidney using anti-BMP2 polyclonal antibody

 

References:
1. Wang, E.A. et al. (1988) Proc Natl Acad Sci USA 85, 9484-8
2. Wozney, J.M. et al. (1988) Science 242, 1528-34.
3. Kawabata, M. et al. (1998) Cytokine Growth Factor Rev 9, 49-61
4. Nohe, A. et al. (2004) Cell Signal 16, 291-9.