Anti-c-kit (CD117)  polyclonal antibody  (Rabbit)               Catalog:0108-4

Product Description: CD117 Antigen, also called KIT or C-kit receptor, is a cytokine receptor expressed on the surface of hematopoietic stem cells as well as other cell types. It has a tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase (Pi3K). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous leukemia, and piebaldism.

Species Cross-reactivity:  Human , Mouse , Rat

Formulation:   0.5 mg/ml

Application(s):   WB: 1:500, ICC: 1:100

Storage Buffer: 1*TBS (pH7.4), 0.5%BSA, 25%Glycerol. Preservative: 0.05% Sodium Azide.
Storage Instruction: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Purity: Immunogen affinity purified


Fig: Western blot analysis on jurkat cell lysates using anti-c-kit polyclonal antibody


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