(CD117) polyclonal antibody
Description: CD117 Antigen, also called KIT or C-kit
receptor, is a cytokine receptor expressed on the surface of
hematopoietic stem cells as well as other cell types. It has a
tyrosine-protein kinase activity. Binding of the ligands leads to
the autophosphorylation of KIT and its association with substrates
such as phosphatidylinositol 3-kinase (Pi3K). Mutations in this
gene are associated with gastrointestinal stromal tumors, mast
cell disease, acute myelogenous leukemia, and piebaldism.
Species Cross-reactivity: Human , Mouse , Rat
WB: 1:500, ICC: 1:100
Storage Buffer: 1*TBS (pH7.4), 0.5%BSA, 25%Glycerol.
Preservative: 0.05% Sodium Azide.
Storage Instruction: Store at +4°C after thawing.
Aliquot store at -20°C or -80°C. Avoid repeated freeze /
Purity: Immunogen affinity purified
Fig: Western blot analysis on jurkat cell
lysates using anti-c-kit polyclonal antibody
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5. Spritz RA, Giebel LB, Holmes SA. (1992) Am J Hum Genet. Feb;5