Description: CD44 is a cell-surface glycoprotein
postulated to play a role in a variety of biological processes,
including lymphocyte homing and tumor-cell metastasis. It mediates
cell-cell and cell-matrix interactions through its affinity for
hyaluronic acid (HA), and possibly also through its affinity for
other ligands such as osteopontin, collagens, and matrix
metalloproteinases (MMPs). Adhesion with HA plays an important
role in cell migration, tumor growth and progression. CD44 is
highly polymorphic, possesses a number of alternative splice
variants and undergoes extensive post-translational modifications.
Species Cross-reactivity: Human
Storage Buffer: 1*TBS (pH7.4), 0.5%BSA, 25%Glycerol.
Preservative: 0.05% Sodium Azide.
Storage Instruction: Store at +4°C after thawing.
Aliquot store at -20°C or -80°C. Avoid repeated freeze /
Purity: Immunogen affinity purified
Fig: Western blot analysis on Hela using
anti-CD44 monoclonal antibody.
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