Anti-Neuron-specific class III β-tubulin polyclonal antibody  (Rabbit)           Catalog:0805-3

Alternative names:TUBB3, TUBB4 ,Tubulin beta-4 chain,Tubulin beta-III,Tubulin beta-3 chain

Product Description: Tubulin is a compound of subunits of A tubulin and B tubulin. Class III beta tubulin (beta III-tubulin) is a vertebrate tubulin isotype specific to the neurons and mammalian testis cells, making it an ideal neuronal marker. Overexpression of class III beta tubulin is associated with the resistances of microtubule-targeted cancer drugs in lung cancer cell lines, breast cancer cell lines, and ovarian tumors.

Species Cross-reactivity:  Human , Mouse , Rat

Formulation:   0.5 mg/ml

Application(s):   WB: 1:5,000-10,000

Storage Buffer: 1*TBS (pH7.4), 0.5%BSA, 25%Glycerol. Preservative: 0.05% Sodium Azide.
 
Storage Instruction: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
 
Purity: Immunogen affinity purified

  

Fig: Western blot analysis on hela cell lysates using anti- tubulin beta-3 polyclonal antibody

 

References:
1. Wang, HW et al. Nature 435: 911-915, 2005.
2. Cleveland, DW et al. Cell 20: 95-105, 1980.
3. Hasegawa S et al. Clin Can Res 9: 2992-2997, 2003.